A 29-year-old man has been diagnosed by the PMHNP with depression, and they have mutually agreed on a trial of an SSRI. The client asks the PMHNP, "Should I stop taking my St. John's Wort?" What is the most appropriate response?

"If you've been taking St. John's Wort and it's not working, an SSRI might not be the best choice. Let's look at other options."

"No, the two actually complement each other well."

"Yes, the interaction between the prescription and St. John's Wort could be life-threatening."

"Maybe you didn't give the St. John's Wort long enough to start working. Give it some more time before you start the SSRI."