Nurse Moose
    PATHOPHYSIOLOGY PROCTORED EXAM JEFFERSON COLLEGE

    A 50-year-old man presents with a 1-cm lesion on the sun-exposed, dorsal surface of his right hand (shown). The black skin reflects trauma and bleeding. Biopsy reveals malignant keratinocytes and "keratin pearls". This neoplasm most likely arose from which of the following preexisting skin conditions?