A client that was recently diagnosed with active tuberculosis is being sent home on combination therapy of Rifampin and Isoniazid. The nurse determines that the client needs additional education if the patient states:

My urine, tears and saliva might turn orange.

I will have to keep taking these medications until I have had three negative sputum cultures.

I can continue to drink alcohol every night with my friends.

I have to take both of these antibiotics, and I might have to be supervised to ensure compliance.