A client with chronic obstructive pulmonary disease (COPD) is experiencing dyspnea and has a low PaO2 level. The nurse plans to administer oxygen as prescribed. Which statement is true concerning oxygen administration to a client with COPD?

Administration of oxygen is contraindicated in clients who are using bronchodilators.

High oxygen concentrations will cause coughing and dyspnea.

Increased oxygen use will cause the client to become dependent on the oxygen.

High oxygen concentration may inhibit the hypoxic stimulus to breathe.