A nurse assesses a client with renal insufficiency and a low red blood cell count. The client asks, "is my anemia related to my kidney problem?" How would the nurse respond?

"Kidney insufficiency inhibits active transportation of red blood cells throughout the blood."

"Red blood cells produce erythropoietin, which increases blood flow to the kidneys."

"Your anemia and kidney problem are related to inadequate vitamin D and a loss of bone density."

"Erythropoietin is usually released from the kidneys and stimulates red blood cell production in the bone marrow.