A nurse at an ophthalmology clinic is providing teaching to a client who has open-angle glaucoma and a new treatment regimen of timolol and pilocarpine eye drops. Which of the following instructions should the nurse provide?

Administer the medications 5 minutes apart.

Administer the medications by touching the tip of the dropper to the sclera of the eye.

Hold pressure on the conjunctival sac for 2 minutes following application of drops.

It is not necessary to remove contact lenses before administering medications.