A nurse at an ophthalmology clinic is providing teaching to a client who has open-angle glaucoma and a new treatment regimen of timolol and pilocarpine eye drops. Which of the following instructions should the nurse provide?

Administer the medications 5 minutes apart.

Hold pressure on the conjunctival sac for 2 minutes following application of drops.

It is not necessary to remove contact lenses before administering medications.

Administer the medications by touching the tip of the dropper to the sclera of the eye.