A nurse is caring for a client who has a bloodstream infection caused by a multidrug-resistant organism (MDRO). The nurse is preparing to administer intravenous vancomycin. Which action should the nurse take to reduce the risk of nephrotoxicity?

Stopping the medication if the client reports nausea or vomiting

Flushing the intravenous line with 0.9% sodium chloride before and after administration

Monitoring the client's serum creatinine and blood urea nitrogen (BUN) levels before each dose

Administering the medication over 15 minutes to reduce infusion-related reactions