A nurse is caring for a client who is experiencing manifestations of anxiety. The nurse should recognize which of the following statements about the neurophysiologic manifestations of anxiety as correct?

The cortico-striato-thalamo-cortical circuit (CSTC) of the brain is associated with phobias.

The cortico-striato-thalamo-cortical circuit (CSTC) of the brain is associated with feelings of fear.

The amygdala-centered (ACC) circuit of the brain is associated with feelings of panic.

The amygdala-centered (ACC) circuit of the brain is associated with feelings of apprehension.