A nurse is developing a care plan for Mrs. Thompson who is in the end-of-life stage. After assessing the client, the nurse has identified several potential problems. Which of the following hypotheses should the nurse prioritize when planning care for this client?

The client may benefit from additional laboratory tests to monitor disease progression.

The client may experience pain and discomfort due to the progression of their illness.

The client may need increased physical therapy sessions to maintain mobility.

The client may have elevated blood pressure due to an acute exacerbation of their condition.