A nurse is providing education to a client who needs a cholecystectomy due to a build-up of calculi or gallstones. Which of the following is the best response from the nurse to explain what caused this problem?

The gallbladder has become blocked by a tumor and is no longer working.

The gallbladder became infected by a virus and needs to be removed.

The gallbladder has become inflamed due to a build-up of gallstones that are blocking the common bile duct.

The gallbladder has become inflamed due to the cholesterol in the gallstones.