A nurse is providing instructions to a client who has a new prescription for sublingual nitroglycerin (Nitrostat) to treat angina pectoris. Which of the following instructions should the nurse include?

"Place the tablet under your tongue"

"The medication can take up to 15 minutes to take effect."

"Stop taking the medication and notify your provider if you develop a headache."

"Avoid taking the medication prior to exercising."