A nurse is providing teaching about the use of metered-dose inhalers to a client who has asthma. Which of the following instructions should the nurse include?

"Hold your breath for 10 seconds after each puff."

"Inhale rapidly for 1 to 2 seconds after depressing the canister."

“Hold the mouthpiece 4 Inches away from your open mouth.”

"Tilt your head forward while inhaling.”