A nurse is providing teaching to a client who has a new prescription for transdermal nitroglycerin patches to treat angina pectoris.Which of the following instructions should the nurse include in the teaching?

“Remove the patch for two to four hours daily.”.

“Apply a new patch each day after waking up.”.

“Cover the patch with plastic wrap.”.

“Replace the existing patch with a new patch as soon as anginal pain begins.”. .