A nurse is providing teaching to a client who has stable angina and a new prescription for transdermal nitroglycerin. Which of the following instructions should the nurse include? (Select all that apply.)

Remove the patch for 10 to 12 hr daily.

Apply the patch to dry skin and cover the area with plastic wrap.

Apply the patch to a hairless area and rotate sites.

Apply a new patch each morning.

Apply a new patch at the onset of anginal pain.