A nurse is reinforcing teaching with a client has a new diagnosis of aplastic anemia. When discussing the pathology of this disease, which of the following instructions should the nurse include in the teaching?

"Aplastic anemia is associated with the decreased intake of iron."

"Aplastic anemia results from decreased bone marrow production of RBCs."

"Aplastic anemia results in an increased rate of RBC destruction."

"Aplastic anemia is directly related to impaired liver function."