A nurse is reinforcing teaching with a client who has a new diagnosis of gout. The client asks the nurse how they got the disorder. What should the nurse include in the teaching?

Tophi form in the adrenals and impair the excretion of uric acid.

Articular cartilage thins, leading to splitting and fragmentation.

Uric acid crystal deposits cause inflammation in joints.

Uric acid levels drop and calcium forms precipitate.