A nurse is teaching a client who has tuberculosis and is to start medication therapy with isoniazid, rifampin, and pyrazinamide. Which of the following instructions should the nurse include?

Provide a sputum specimen every 2 weeks to the clinic for testing

Expect your sputum cultures to be negative after 6 months of therapy

Drink at least 8 ounces of water when you take the pyrazinamide tablet

Take isoniazid with an antacid