A nurse is teaching a client who is at 16 weeks of gestation about the alpha-fetoprotein test. Which of the following information should the nurse include in the teaching?

The alpha-fetoprotein test identifies a risk for ABO incompatibility

The provider will draw the alpha-fetoprotein sample from an umbilical vein

The alpha-fetoprotein test screens for neural tube defects

The provider will collect the alpha-fetoprotein sample during an amniocentesis