A nurse is teaching a group of nurses about the importance of prophylactic antimicrobial therapy. Which information should the primary nurse include in the teaching? (Select All That Apply).

Administer a prophylactic antimicrobial therapy to clients after being diagnosed with a respiratory infection.

Instruct clients who have a prosthetic heart valve about the need for prophylactic antimicrobial therapy before dental work.

Instruct clients to request prophylactic antimicrobial therapy when they have an upper respiratory infection.

Administer a prophylactic antimicrobial therapy to clients who are having an orthopedic surgery.