A nurse is teaching the parents of a pediatric client who has been diagnosed with systemic juvenile idiopathic arthritis (JIA) about long-term effects. Which of the following statements should the nurse include in their teaching?

"JIA can cause joint damage leading to permanent deformities and reduced mobility."

"JIA has no long-term developmental effects as long as it is treated with NSAIDS."

The inflammation of the joints experienced with this type of JIA is mild."

"Most children do not need any treatment beyond monitoring, and they will grow out of this type of JIA."