A nurse manager in a health clinic is discussing complications associated with sexually transmitted infections (STIs) with a newly licensed nurse. Which of the following statements should be included in the discussion?

"A complication of syphilis during pregnancy is low-birth-weight infants."

"Human papillomavirus can lead to cancer of the cervix."

"A complication of chlamydia in males is meningitis."

"Herpes simplex virus can lead to pelvic inflammatory disease."