A patient with a respiratory infection asks the nurse why some antibiotics are prescribed to be given every 12 hours while others have to be taken 4 times per day. What is the nurse's best response?

"We need to vary the times of administration to keep the blood levels fluctuating"

"The time between medication varies to fit the nurse's schedule"

"Regular doses are given based on the half-life of the medication to maintain a therapeutic effect"

"We try to give the next dose of medication only after the last dose is gone"