A patient with persistent, frequent asthma exacerbations asks a nurse about a long-acting beta2-agonist medication. What will the nurse tell this patient?

LABAs reduce the risk of asthma-related deaths.

LABAs can be used on an as-needed basis to treat symptoms.

LABAs are safer than short-acting beta2 agonists.

LABAs should be combined with an inhaled glucocorticoid.