A public health nurse is assisting with the recruitment of Black men for a research study on coronary artery disease. Which of the following reasons explains the importance for the nurse to have knowledge of the Tuskegee Syphilis Study?

The Tuskegee Syphilis Study demonstrated a correlation between coronary artery disease and syphilis.

The Tuskegee Syphilis Study excluded Black men.

The Tuskegee Syphilis Study is a source of distrust and a barrier to Black clients participating in research studies.

The Tuskegee Syphilis Study provides guidelines for recruitment of Black and African-American research participants.