A public health nurse is recruiting Black men for a research study on coronary artery disease. Which of the following reasons explains the importance for the nurse to have knowledge of the Tuskegee Syphilis Study?

The Tuskegee Syphilis Study provides guidelines for recruitment of Black and African-American research participants.

The Tuskegee Syphilis Study demonstrated a correlation between coronary artery disease and syphilis.

The Tuskegee Syphilis Study excluded Black men.

The Tuskegee Syphilis Study is a source of distrust and a barrier to Black clients participating in research studies.