A school nurse is teaching the guardians of adolescents about the importance of the human papillomavirus (HPV) vaccine. Which of the following information should the nurse include?

Reassure the parents that HPV is a rare infection and the vaccine is unnecessary.

Instruct the guardians to wait until their adolescent tells them they have been sexually active to vaccinate.

Explain that only female adolescents should receive the HPV vaccine.

Provide information to guardians about the prevalence of HPV infections and the potential consequences.