The nurse is discussing insulin administration with an assigned patient. The patient reports that she prefers to use only certain sites for insulin injections. The patient questions why rotation of the sites is important. What response by the nurse is most appropriate?

"Unsightly fatty tumors can develop when you do not adequately rotate injection sites."

"Rotating your injection sites will help to reduce your risk of infection."

"Failing to rotate injection sites will improve your ability prevent an insulin reaction."

"Rotating your injection sites will help to reduce your risk for lipodystrophy."