The nurse reviews a primary health care provider’s prescriptions and notes that a topical nitrate is prescribed. The nurse notes that acetaminophen is prescribed to be administered before the nitrate. The nurse implements the prescription with which understanding about why acetaminophen is prescribed?

Fever usually accompanies myocardial infarction.

Acetaminophen does not interfere with platelet action as acetylsalicylic acid (aspirin) does.

Headache is a common side effect of nitrates.

Acetaminophen potentiates the therapeutic effect of nitrates.

Acetaminophen potentiates the therapeutic effect of nitrates.