The nurse teaches a new registered nurse who is preparing to administer packed red blood cells to a client. Which action by the new registered nurse requires immediate intervention?

Starting an IV line for the transfusion using a 20-gauge catheter.

Priming the transfusion set using normal saline.

Waiting 45 minutes after obtaining the packed red blood cells before starting the infusion.

Telling the patient that the packed red blood cells may cause a serious transfusion reaction.