The spouse of a patient diagnosed with bipolar disorder asks what evidence supports the possibility of genetic transmission of bipolar disorders Which response should the nurse provide?

"A high proportion of patients with bipolar disorders are found among creative writers"

"A higher rate of relatives with bipolar disorder is found among patients with bipolar disorder"

"More individuals with bipolar disorder come from high socioeconomic and educational backgrounds"

"Patients with bipolar disorder have higher rates of relatives who respond in an exaggerated wary to daily stress"