Non-Hodgkin's lymphoma is more commonly associated with painless, enlarged lymph nodes than Hodgkin's lymphoma
Hodgkin's lymphoma presents with a more aggressive course than Non-Hodgkin's lymphoma
Non-Hodgkin's lymphoma typically involves the reed-Sternberg cells
Hodgkin's lymphoma usually has a more predictable and localized spread than Non-Hodgkin's lymphoma