Which of the following nursing interventions are crucial in preventing ventilator-associated pneumonia in a client on mechanical ventilation? Select all that apply.

Elevating the head of the bed to 30-45 degrees

Conducting frequent repositioning and mobilizing the client as tolerated

Ensuring the ventilator settings are adjusted every eight hours exactly

Performing regular oral hygiene with mouth rinses and suctioning secretions

Administering pantoprazole 40 mg IVP daily