Which statements made about theophylline by a patient with asthma would alert the nurse that further intervention is warranted? (Select all that apply)

I should avoid smoking and being around smoke while I am taking the drug.

I should take an extra dose during an asthma attack.

If I accidentally miss a dose, I can double up on my next dose.

I should avoid caffeine as much as possible while receiving theophylline.

I will routinely follow up with my health care provider to have my drug levels determined.