Which treatment best applies to the care of a client newly diagnosed with infective endocarditis?

Complete bedrest for the duration of the treatment with subcutaneous enoxaparin.

Long-term anticoagulant therapy with IV heparin followed by oral warfarin.

Administration of IV penicillin, followed by oral penicillin for 10 weeks.

Hospitalization for initial IV antibiotics, followed by continued IV antibiotics at home.